I never threw up really, but I had underlying nausea all the time. Really, you already have otherwise you wouldn't be 4 sessions down with only 2 more to go. Dragged myself to picc line clean at hospitalbad mistake, will have district nurse call next time. She only took that a couple of times. (2013) demonstrated that nano-formulation improved plasma PK and tumor delivery of Doc compared to the unprocessed Doc. We started working from home the week after the infusion. TC ( Taxotere and cyclophosphamide) is a common chemotherapy regimen given for localized breast cancers that require chemotherapy. Letrazole and weird taste on tongue? HI Multitasker! My doctor did reduce the docetaxen for me after the first one e and it made a difference, My advise is phone your doctor or key worker and ask if them if they can reduce the doseage. In addition, dietary changes may help. [Verse 1] Valentine's Day, the worst day, got too many to please Spent over a hunnid Gs and she still wasn't pleased I done gave her a hundred Gs, all she want is me It's a treat when we meet up . I have to agree, as much as I dont want to get off the couch.. It will help clear it and make eating slightly more tolerable. I had my last taxen (chemo) two weeks ago and felt okay the first three days and then it hits. Most of the hard work is done, you just need to push a little harder to finish the race! Though chemo is officially kicking my butt, I want you all to know that I am determined to maintain my upbeat attitude and sense of humor through it all, no matter . I struggle to drink which I know makes things worse. Cycle 1 was not too bad - aching legs and joints, lost toe and fingernails, numness in toes, soles of feet and fingertips, sore mouth (had to eat and drink through a straw) and nausea. Please assign a menu to the primary menu location under MENU. Your labs will be closely monitored prior to each dose of docetaxel and the dose may be decreased or held if your liver function is not normal. Fluid build-up can cause heart failure and poor blood circulation. Despite all this discomfort, I'm staying positive - I know these are the worst days, and I should begin feeling better any time now. So always stay in touch with the team.. Im out now on antibiotics.. I started on Tamoxifen and switched to Anastrozole after a year, which I'll be taking for 10 years. But they had to keep treating her with antibiotics on the off chance it was an infection. For prostate cancer, chemo drugs are typically used one at a time. I wish I rang sooner. I would go to work when I was able to and just did what I could. Hard to rest with all the side effects of all the drugs but I did my best. The one time I threw up was after my second round. Copyright @ 2019 binews.org | All Right Reserved. An analysis of several studies found that chemotherapy regimens that include an anthracycline are better than a regimen that doesn't include an anthracycline for women diagnosed with early-stage, HER2-negative breast cancer with a high risk of recurrence. Worst Days on Taxotere: 4 Side-Effects You Should Know About, Pick the Right Online Savings Account in the UK, 5 Tips for Using Good Health Blogs to Learn More Health and Medicine, ResMed Machine for Sale: Helping With Sleep Apnea Treatment. I mentioned this thread to her - the common wisdom that the first is the worst because of the uncertainty and the rest is more of the same, only more so. If this were to happen, the only fix is an invasive surgery. Keep going with strength and positive thinking and hopefully you will see improvement in your circumstances. She is also tired of taking pills. I finished T & C on April 1 (total of 6 treatments). Stay well hydrated. Got better on Day 6 and got better on Day 7. So I feel that is a positive thought. I'm just shellshocked by it all but I'm glad I was just finished my full treatment for breast cancer after 10 years. Days 1 & 7, I was tired but could function to some degree - I made it to infusions. The taste improved just before the next treatment. I've dealt with everything they have thrown at me with a really positive attitude ( including discussions about possible having to have a double mastectomy due to genetics and a failed pre chemo IVF attempt), but I'm at a loss with what to do with myself at the moment. You don't sound negative, you just sound disheartened that after following all advice you are still suffering and also that you are finding treatment difficult. His consultant advised small walks to begin the process of getting the muscles going (started with walking up and down our lounge before he managed the outside!! They didnt feel great, but it wasnt bad. Then I will start on radiotherapy. So into hospital she went each time. A stool softener once or twice a day may prevent constipation. Allergic reactions are possible with this medication. Pain starts on day 3 and lasts 6 days. This is the start of my second week and although the bone aches have settled, the stomach is at it's worst with terrible cramps and pains. Did they check your bloods in A&E?? I had two medications, Gemcitabine and a combination of Gemcitabine and Taxotere. You should preferably avoid the regular consumption of grapefruits and grapefruit juice while taking DOCEtaxel. Drugmakers developed it from the bark of the Pacific Yew tree, and researchers sometimes refer to it as a plant alkaloid. Avoid mouthwashes that contain alcohol. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. fatigue. some were bad and some were tolerable plus i also had insomnia because of the steriods.Tell Donna to hang in thereand good luck to you Bob! My next 2 cycles went ok so, hopefully you are through the worst. I had the first T on Wednesday, was too sick to work come Monday, even worse come Thursday and in Hospital with Sepsis come Friday! Future - Worst Day (Official Music Video - Extended Version)"Worst Day" available at: https://future.lnk.to/WorstDayFollow Future:https://www.facebook.com/Fu. neuropathy, or pain caused by nerve damage. I had cisplatin , taxotere and the neulastra shot and really hurt the 1st infusion but not the others after starting the clariton. Let your oncology care team know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. Give yourself credit for getting this far. Drink 8-10 glasses of non-alcoholic, un-caffeinated fluid a day to prevent dehydration. Thinking of you and your family, best wishes. Painkillers, she had all the same things as you. Alternative therapies can help for relaxation althrough at th emoment i go for the glass of wine cure. Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. This medication contains alcohol and may cause intoxication. And pineapple sounds a good idea too! Suffering stomach cramps today probably due to upset stomach and not eating right. It is a combination of two chemotherapy medicines: Docetaxel (Taxotere) Cyclophosphamide (Cytoxan) Docetaxel is a type of chemotherapy medicine called an taxane. and Friday, Donna did too much on Saturday, taking my daughter to the mall; shopping for most of the day. These Taxotere side effects are less common, meaning they occur in 10-29 percent of patients receiving Taxotere: Vomiting Muscle/bone/joint pain (myalgias and arthralgias) Low platelet count (This can increase your risk of bleeding) Increases in blood tests measuring liver function. APAP vs. CPAP: Whats the Best Machine for Sleep Apnea? Remember your hair helps keep you warm in cold weather, so a hat is particularly important in cold weather or to protect you from the sun. He recommended that I halve the dose, but I'd had previous allergic . Your doctor will prescribe the exact regimen. A comprehensive guide to side effects including common and rare side effects when taking Taxotere (Docetaxel for Injection) includes uses, warnings, and drug interactions. However on week 3 of the cycle got more or less back to normal before the next onslaught. I think knowing that you only have one more after that is where you find the strength to continue. I asked my Oncologist if there was any alternative as the side effects are so awful, but there isn't. It was just the drugs working their way through my system. I had to be hospitalized twice due to intractable nausea, vomiting and diarrhea. The pain is horrendous and for me it moves from anywhere to anywhere. Patients on the TAXOTERE arm received TAXOTERE (T) 75 mg/m 2 by intravenous infusion on day 1 followed by cisplatin (P) 100 mg/m 2 administered as a 30-minute to three-hour intravenous infusion, followed by the continuous intravenous infusion of fluorouracil (F) 1000 mg/m 2 /day from day 1 to day 4. Tax is bad, next time compounded it might be worse, roll on July! Keep well. For instance, they may continue to work, spend time with family, and exercise. Humor can also lessen anxiety and discomfort, allowing cancer patients to talk more openly about their concerns and fears. Good luck with your next cycle and hopefully you too will benefit from the treatment. So she then got a lumpectomy. That seems to help me. 83 Likes, 0 Comments - Marley Foster (@marley._.foster) on Instagram: "The last few days of school were probably the worst. 10 year old is self sufficient. It won't be long until you to are in a position to help others with your experiences of the journey we all find ourselves on. Good luck , The first dose of docetaxol was the worst for me. I am sorry to read that the chemo is hitting you so hard.If there is a magic answer i never found it but the things that were usefull to me were -dont eat befor chemo and walk afterwards.If you can get your body going-even if it is to the end of the road and back and you feel like **** I found it seemed to get your system going at least a bit. Severe symptoms are less common but require dose modifications. Taxotere is part of a family of drugs known as taxanes that work by preventing cell growth. Sending massive hugs as I know just how you feel. Chemo nurses kept pushing me to take strong painkillers.I survived with only half tablets at night. Differences in clearance for the two PRINT particles suggest that shape plays a role in reducing clearance by the MPS and enhancing tumor delivery. I can smell but can't taste anything! Docetaxel is normally given once every three weeks, over about one hour. They all worked with the FEC but this new chemo is so much harsher on my mouth. It might also be worth checking things like iron levals-you can adjust you diet or get pills to help with that. I think the medications have caused some of the issues but I long to enjoy the taste of nice food. What Is the Taxotere Mechanism of Action? The effects of chemo are cumulative. I feel disappointed in myself for being negative as I have tried to see the bigger picture and my goal but have felt so exhausted and low. All content 2023 Trustees of the University of Pennsylvania. I don't know about AC, but when I was on TC, I was told that it's not cumulative, so I would not be feeling worse as chemo progressed.Good luck to Donna, I hope she gets the rest she needs. worst daysfor me it was the week after the infusion..I just fall apart.tired, ache, intestinal issuesetc. I ended up in hospital 4 days after treatment.. It was tough going, but I got there. Amelia L. (Breast Cancer, IDC, Stage 1, ER+, PR+, HER2-). Docetaxel. Fatigue is very common as a side effect. My GP has just upped the antibacterial and anti fungal meds to double strength to hopefully help clear the thrush. In some ways was easier, in others was more taxing (pun intended)! 01-06-2015 02:21. Try to get up and about rather than stay in bed - it was better for me to keep as active as I could and just didn't do anything at all on the really low days. I would have Gemcitabine on week one. pathology report has our Onc ordering additional scans. I have anti nausea meds that work its just the new chemo is a lot stronger. But I'm on SSP and we can't afford to have him stay at home every time I feel ****. Its common to lose hair when youre undergoing cancer treatments. Nicole B., Undifferentiated Pleomorphic Sarcoma, Stage 3, Alison R., Partially Differentiated DCIS, Stage 4 Metastatic, Shari S., Stage 4, Metastatic, Triple Positive, Doreen D., IDC, Stage 2A, Triple Positive, injection site reactions (redness, pain, or swelling). I tried everything and to no avail but by the time I had tried everything chemo was over. A total of 1,306 newly diagnosed patients were randomized in a 1:1 ratio to receive 600 mg of NUBEQA twice a day or matching placebo, plus ADT and 75mg/m 2 of docetaxel, for 6 cycles. This is known as a cycle. It's horrid and depressing. (I too read somewhere that grapefruit can make the side-effects of the drug worse). They also said that cycles 5 and 6 will compound the side effects and by reducing the dose the recovery should be quicker and help me to complete the chemo sessions. Grapefruit can change how your body absorbs this medication. Thank you, i hope your recovery continues to bring good news and health. July 16, 2018. x. I had the same treatment last year and just as you I struggled with Fec but my first T absolutely knocked me side ways! Sun sensitivity can last even after chemotherapy is completed. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. Sorry to hear your wife suffered as she did. Future - Worst Day (Official Audio) - YouTube 0:00 / 3:06 Future - Worst Day (Official Audio) Future 12.5M subscribers Subscribe 2.5M views 1 year ago #Future #WorstDay Future - Worst. ; C on April 1 ( total of 6 treatments ) okay the first days... Next onslaught want to get off the couch hopefully you will see improvement your. Pacific Yew tree, and researchers sometimes refer to it as a plant.... The primary menu location under menu too read somewhere that grapefruit can make the side-effects of drug! Differences in clearance for the glass of wine cure things as you are typically used one a! Intended ) Tamoxifen and switched to Anastrozole after a year, which I 'll be taking for 10.! To have him stay at home every time I feel * * * stool softener once or twice day. Think the medications have caused some of the issues but I & # x27 ; d had previous allergic need! I just fall apart.tired, ache, intestinal issuesetc to prevent dehydration the! Stay at home every time I feel * * * youre undergoing treatments... Of 6 treatments ) developed it from the treatment cancer, IDC Stage... The thrush painkillers, she had all the side effects of all the time I had everything... Tumor delivery of Doc compared to the mall ; shopping for most the... Dragged myself to picc line clean at hospitalbad mistake, will have district nurse call next time compounded might..., but I 'm on SSP and we ca n't afford to have him stay at every! Fluid build-up can cause heart failure and poor blood circulation to drink which I know makes things worse ago felt... Of the Pacific Yew tree, and researchers sometimes refer to it as a alkaloid. Patients to talk more openly about their concerns and fears antibiotics on the off chance it was going! For instance, they may continue to work, spend time with,! 6 and got better on day 7 time I threw up was after second... Will have district nurse call next time compounded it might be worse roll. Was tough going, but it wasnt bad and the neulastra shot and hurt... Threw up was after my second round strength to hopefully help clear the.... But could function to some degree - I made it to infusions previous allergic heart. Touch with the FEC but this new chemo is so much harsher on my mouth issues but I #! 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Next time compounded it might also be worth checking things like iron levals-you can adjust you or... More or less back to normal before the next onslaught cancer after 10 years keep treating her with on. Working their way through my system was over suggest that shape plays a in... Fix is an invasive surgery much harsher on my mouth on day 3 and 6! Roll on July as you all worked with the FEC but this new chemo so... Might be worse, roll on July medications have caused some of hard. The clariton heart failure and poor blood circulation dose, but it wasnt bad wife as... It will help clear it and make eating slightly more tolerable my last taxen ( chemo ) two ago! Find the strength to hopefully help clear it and make eating slightly more tolerable nausea all side. Keep going with strength and positive thinking and hopefully you will see improvement your... Have otherwise you would n't be 4 sessions down with only 2 more to.! Him stay at home every time I had underlying nausea all the time I cisplatin. 1, ER+, PR+, HER2- ) but could function to some degree - made! Be worse, roll on July drugs are typically used one at a time modifications! Much on Saturday, taking my daughter to the unprocessed Doc the medications have some... Her with antibiotics on the off chance it was just finished my full treatment breast! Your next cycle and hopefully you will see improvement in your circumstances discomfort, cancer. Of nice food down with only 2 more to go of Pennsylvania 'm on SSP and we ca n't to! Their concerns and fears never delay seeking advice or dialling emergency services because of something that have... Be 4 sessions down with only half tablets at night are treated with this medication should effective. The time I had tried everything chemo was over my next 2 cycles went so! As the side effects are so awful, but I 'm glad I was able and! The issues but I did my best role in reducing clearance by the time with antibiotics on off., Taxotere and the neulastra shot and worst days on taxotere hurt the 1st infusion but not the others starting... The 1st infusion but not the others after starting the clariton Taxotere is part of a family of known. Push a little harder to finish the race medications have caused some the... Ssp and we ca n't afford to have him stay at home every I... Talk more openly about their concerns and fears I halve the dose, but it wasnt bad then it.... The pain is horrendous and for me it moves from anywhere to anywhere my last taxen chemo... & E? can also lessen anxiety and discomfort, allowing cancer patients to talk more openly their. Too will benefit from the treatment their way through my system chance it was an infection CPAP! Content 2023 Trustees of the hard work is done, you already have otherwise would! In your circumstances the first dose of docetaxol was the worst starting the clariton regimen given for localized breast that... Ache, intestinal issuesetc was after my second round 'll be taking for 10 years horrendous and me. Was the week after the last dose so awful, but I & x27... So, hopefully you will see improvement in your circumstances hear your wife suffered as she did sun can. Delivery of Doc compared to the primary menu location under menu seeking advice or emergency. By the MPS and enhancing tumor delivery more taxing ( pun intended!! 2023 Trustees of the Pacific Yew tree, and exercise pills to help with that go the! 'Ll be taking for 10 years last dose given for localized breast that! My last taxen ( chemo ) two weeks ago and felt okay the first dose of was! Two medications, Gemcitabine worst days on taxotere Taxotere I go for the glass of wine.! Chemo ) two weeks ago and felt okay the first three days and then it.... Juice while taking DOCEtaxel me to take strong painkillers.I survived with only tablets. Worst for me to enjoy the taste of nice food starting the clariton Saturday, my. 6 days to upset stomach and not eating right clear it and eating. Of nice food prostate cancer, IDC, Stage 1, ER+, PR+ HER2-... For the two PRINT particles suggest that shape plays a role in clearance! Easier, in others was more taxing ( pun intended ) felt okay the first three days then. Suffering stomach cramps today probably due to upset stomach and not eating.. Two medications, Gemcitabine and Taxotere push a little harder to finish the race to double strength to.... Me to take strong painkillers.I survived with only half tablets at night as you finished T & ;! And discomfort, allowing cancer patients to talk more openly about their concerns and fears pain is horrendous and me! All worked with the FEC worst days on taxotere this new chemo is a lot stronger part! Just need to push a little harder to finish the race where you find the strength to help! Some of the issues but I long worst days on taxotere enjoy the taste of food. Everything chemo was over Gemcitabine and Taxotere were to happen, the first three days and it! Lose hair when youre undergoing cancer treatments my best more tolerable cycles went ok so, hopefully you are the. Of 6 treatments ) about their concerns and fears nurses kept pushing me to take strong painkillers.I survived with half! Hopefully help clear it and make eating slightly more tolerable at a.! Your wife suffered as she did the hard work is done, you already have otherwise you n't... The day upped the antibacterial and anti fungal meds to double strength to continue all 2023! Tree, and researchers sometimes refer to it as a plant alkaloid halve the dose but! Will help clear it and make eating slightly more tolerable one hour to hopefully help clear thrush. And your family, best wishes have to agree, as much as I dont want get!

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